Description

(1S,2S)-2-Amino-1-Phenylpropyldiphenylphosphine, Min. 97% is a high-purity chiral phosphine ligand and organocatalyst essential for asymmetric synthesis. This compound matters because it enables the precise control of stereochemistry in pharmaceutical and fine chemical manufacturing, leading to higher yields of enantiomerically pure products. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and specialty chemicals.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric hydrogenation and cross-coupling reactions.
• As a key organocatalyst in the enantioselective synthesis of pharmaceutical intermediates, such as β-amino acids and amines.
• For the development of asymmetric synthetic methodologies in academic and industrial research laboratories.
• In the production of enantiomerically pure compounds for use in drug discovery and development pipelines.
• As a building block for more complex, tailor-made phosphine ligands with specific steric and electronic properties.

Basic Information

Item	Details
Product Name	(1S,2S)-2-Amino-1-Phenylpropyldiphenylphosphine, Min. 97%
CAS No.	341968-71-6
Molecular Formula	C21H22NP
Molecular Weight	319.38 g/mol
Synonyms	(1S,2S)-(-)-2-Amino-1-phenyl-1-propyldiphenylphosphine; (1S,2S)-2-Amino-1-phenylpropyldiphenylphosphine; (S,S)-2-Amino-1-phenylpropyldiphenylphosphine; (1S,2S)-APDPP; (S,S)-APDPP; (1S,2S)-(-)-APDPP; Chiral APDPP ligand; (S,S)-2-Amino-1-phenyl-1-propyldiphenylphosphine
EINECS	Contact for details

Quality Control

Our (1S,2S)-2-Amino-1-Phenylpropyldiphenylphosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure a minimum purity of 97% and correct stereochemical integrity. Certificates of Analysis (COA) with full analytical data are provided to guarantee consistent quality and traceability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Water Content (KF)	Max. 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.