Description

(S)-4-(4-Nitro-Benzyl)-Oxazolidin-2-One CAS NO 340041-92-1 is a high-purity chiral oxazolidinone derivative, a critical building block in modern asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and a key intermediate for constructing complex, biologically active molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those working on novel active pharmaceutical ingredients (APIs) and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly in antibiotic and central nervous system (CNS) therapeutic research.
• Asymmetric Synthesis: Employed as a chiral auxiliary to induce stereoselectivity in aldol, alkylation, and Diels-Alder reactions.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides where specific stereochemistry is required for efficacy.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and catalysis studies within university and corporate laboratories.
• Fine Chemical Production: Serves as a precursor for other high-value, specialty chemicals requiring the (S)-oxazolidinone framework.

Basic Information

Product Name	(S)-4-(4-Nitro-Benzyl)-Oxazolidin-2-One
CAS No.	340041-92-1
Molecular Formula	C10H10N2O4
Molecular Weight	222.20 g/mol
Synonyms	(S)-4-(4-Nitrobenzyl)oxazolidin-2-one; (S)-4-(p-Nitrobenzyl)-2-oxazolidinone; (4S)-4-[(4-Nitrophenyl)methyl]-1,3-oxazolidin-2-one; (S)-4-(4-Nitrobenzyl)-2-oxazolidinone; (S)-NOB Oxazolidinone; (S)-p-Nitrobenzyl Oxazolidinone; Chiral Evans Auxiliary Derivative
EINECS	Contact for details

Quality Control

Our (S)-4-(4-Nitro-Benzyl)-Oxazolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.