Description

3-(4-Fluoro-Phenyl)-Isoxazole-4-Carboxylic Acid is a high-purity fluorinated isoxazole derivative, a crucial heterocyclic building block in modern synthetic chemistry. Its value lies in its versatile reactivity, serving as a key precursor for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used as a building block in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated isoxazole scaffold.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic structure and functional groups.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	3-(4-Fluoro-Phenyl)-Isoxazole-4-Carboxylic Acid
CAS No.	334930-07-3
Molecular Formula	C10H6FNO3
Molecular Weight	207.16 g/mol
Synonyms	4-Isoxazolecarboxylic acid, 3-(4-fluorophenyl)-; 3-(p-Fluorophenyl)-4-isoxazolecarboxylic acid; 3-(4-Fluorophenyl)-1,2-oxazole-4-carboxylic acid; 4-Carboxy-3-(4-fluorophenyl)isoxazole; 334930-07-3; 3-(4-Fluorophenyl)isoxazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-Phenyl)-Isoxazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.