Description

5-Bromobenzofuran-2-Ylboronic Acid CAS NO 331833-99-9 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and advanced functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, especially those containing benzofuran scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific halogenated heterocyclic architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLEDs and semiconductors, through palladium-catalyzed polymerization or functionalization.
• Chemical Biology & Probe Development: Employed in synthesizing molecular probes and tags for studying biological processes due to its selective coupling capability.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in cross-coupling chemistry and the exploration of new synthetic pathways.
• Ligand & Catalyst Preparation: Can be utilized to synthesize sophisticated bidentate or polydentate ligands for catalysis.

Basic Information

Product Name	5-Bromobenzofuran-2-Ylboronic Acid
CAS No.	331833-99-9
Molecular Formula	C8H6BBrO3
Molecular Weight	240.85 g/mol
Synonyms	(5-Bromobenzofuran-2-yl)boronic Acid; 2-(5-Bromobenzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (Pinacol Ester Precursor); 5-Bromo-2-boronic Acid Benzofuran; B-(5-Bromo-2-benzofuranyl)boronic Acid; 5-Bromobenzofuran-2-boronic Acid; 331833-99-9; 5-Bromo-benzofuran-2-ylboronic acid
EINECS	Contact for details

Quality Control

Our 5-Bromobenzofuran-2-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.