Description

Diphenyl[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]phosphine oxide is a high-value organoboron reagent featuring a phosphine oxide moiety, making it a versatile building block in advanced synthetic chemistry. This compound is specifically engineered to facilitate Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for forming carbon-carbon bonds under mild conditions. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise functionalization of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl scaffolds common in drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages for optimal bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a crucial monomer for constructing electron-transport or host materials in OLED displays and lighting due to its combined boronic ester and phosphine oxide functionalities.
• Ligand Synthesis for Catalysis: The phosphine oxide group can be reduced to form novel phosphine ligands for transition metal catalysis, enabling new reaction pathways.
• Polymer & Material Science: Incorporated into polymers to modify thermal stability, electronic properties, or to create functional materials for sensors and optoelectronics.
• Academic & R&D: A valuable tool for synthetic organic chemists in academia and contract research organizations exploring new coupling methodologies and complex molecule synthesis.

Basic Information

Product Name	Diphenyl[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]phosphine Oxide
CAS No.	328917-29-9
Molecular Formula	C30H30BFO3P
Molecular Weight	508.34 g/mol
Synonyms	(3-(Diphenylphosphoryl)phenyl)boronic acid pinacol ester; [3-(Diphenylphosphinyl)phenyl]boronic acid pinacol ester; 3-(Diphenylphosphoryl)benzeneboronic acid pinacol ester; 2-[3-(Diphenylphosphoryl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)diphenylphosphine oxide; Diphenyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)phosphine oxide
EINECS	Contact for details

Quality Control

Our production of Diphenyl[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]phosphine oxide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is characterized by advanced analytical techniques including NMR (¹H, ¹³C, ³¹P), HPLC, and mass spectrometry. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation during use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.