Description

Androstene-3,17-Dione-2,3,4-13C3 is a high-purity, stable isotope-labeled derivative of androstenedione, a key steroid hormone intermediate. This compound is specifically designed for use as an internal standard in quantitative mass spectrometry, providing unmatched accuracy and reliability in analytical workflows. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, clinical diagnostics, and anti-doping sectors who require precise measurement of steroid hormones and their metabolites.

Application

• Quantitative Mass Spectrometry (LC-MS/MS, GC-MS): Serves as a critical internal standard for the accurate quantification of endogenous androstenedione and related steroid metabolites in complex biological matrices.
• Pharmaceutical R&D and Metabolism Studies: Used in drug discovery and development to trace metabolic pathways, study enzyme kinetics (e.g., aromatase), and investigate steroidogenesis.
• Clinical Diagnostics and Endocrinology: Enables precise measurement of steroid hormone levels in serum, plasma, and urine for diagnosing endocrine disorders such as congenital adrenal hyperplasia (CAH) and polycystic ovary syndrome (PCOS).
• Anti-Doping Analysis: A vital reference material in sports drug testing laboratories for the detection and confirmation of exogenous anabolic androgenic steroids and their metabolites.
• Biochemical Research: Applied in in vitro assays to study steroidogenic enzyme activity and inhibition, providing insights into hormonal regulation and related diseases.
• Forensic Toxicology: Supports the definitive identification and quantification of steroid compounds in forensic investigations.

Basic Information

Product Name	Androstene-3,17-Dione-2,3,4-13C3
CAS No.	327048-86-2
Molecular Formula	C19H2613C3O2
Molecular Weight	~293.4 g/mol
Synonyms	4-Androstene-3,17-dione-2,3,4-13C3; Androst-4-ene-3,17-dione-2,3,4-13C3; [2,3,4-13C3]-4-Androstene-3,17-dione; 13C3-Androstenedione; Isotope-labeled Androstenedione; 13C3-AED; 13C3-4-AD
EINECS	Contact for details

Quality Control

Every batch of Androstene-3,17-Dione-2,3,4-13C3 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive characterization by NMR, MS, and HPLC to ensure identity, potency, and isotopic enrichment. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic purity, and related substances are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storing desiccated at -20°C is recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 99 atom % 13C
Isotopic Enrichment	≥ 99% at positions 2,3,4
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.