Description

(1R)-1-(3,4-Dimethoxyphenyl)-1,2-Ethanediol CAS NO 326491-79-6 is a high-purity chiral diol intermediate characterized by its specific stereochemistry and dimethoxyphenyl functional group. This compound is critical for ensuring the enantiomeric purity and desired biological activity in advanced pharmaceutical syntheses. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or resolving agent in stereoselective chemical reactions to control the formation of specific stereocenters.
• Fine Chemical Production: Serves as a precursor for the manufacture of complex ligands, catalysts, and other specialty organic compounds.
• Research & Development: Used in academic and industrial R&D for method development, process chemistry, and exploring new synthetic pathways.
• Agrochemical Synthesis: Potential intermediate in the development of chiral pesticides or herbicides where specific stereochemistry impacts efficacy.

Basic Information

Product Name	(1R)-1-(3,4-Dimethoxyphenyl)-1,2-Ethanediol
CAS No.	326491-79-6
Molecular Formula	C10H14O4
Molecular Weight	198.22 g/mol
Synonyms	(R)-1-(3,4-Dimethoxyphenyl)ethane-1,2-diol; (1R)-1-(3,4-Dimethoxyphenyl)-1,2-ethanediol; (R)-HMS; (R)-1,2-Dihydroxy-1-(3,4-dimethoxyphenyl)ethane; (R)-3',4'-Dimethoxyphenylglycol; (R)-DMPG; (R)-1-(3,4-Dimethoxyphenyl)glycol; (R)-α,β-Dihydroxy-3,4-dimethoxyhydrocinnamic alcohol
EINECS	Contact for details

Quality Control

Our (1R)-1-(3,4-Dimethoxyphenyl)-1,2-Ethanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.