Description

2,2'-((1R,2R)-1,2-Cyclohexanediylbis((E)-nitrilomethylylidene))bis(4,6-di-tert-butylphenol) is a high-purity, chiral salen-type ligand with significant utility in asymmetric catalysis and materials science. Its rigid, well-defined stereochemistry makes it a critical component for researchers and manufacturers seeking to impart enantioselectivity in complex synthetic transformations. This compound is primarily sought after by the pharmaceutical, agrochemical, and fine chemical industries for the development of novel catalytic processes and advanced functional materials.

Application

• As a chiral ligand in asymmetric catalysis, including epoxidation, cyclopropanation, and hydroxylation reactions.
• Key intermediate in the synthesis of advanced metal-organic frameworks (MOFs) and coordination polymers with specific optical properties.
• Utilized in the research and development of novel pharmaceutical intermediates requiring high enantiomeric purity.
• Component in the preparation of stereoselective catalysts for agrochemical active ingredient synthesis.
• Building block for functional materials used in sensors and nonlinear optics (NLO).
• As a chelating agent in analytical chemistry for the separation and detection of metal ions.

Basic Information

Product Name	2,2'-((1R,2R)-1,2-Cyclohexanediylbis((E)-nitrilomethylylidene))bis(4,6-di-tert-butylphenol)
CAS No.	323193-85-7
Molecular Formula	C38H56N2O2
Molecular Weight	572.86 g/mol
Synonyms	(R,R)-(-)-1,2-Cyclohexanediamino-N,N'-bis(3,5-di-tert-butylsalicylidene); (R,R)-Jacobsen's Ligand (Salen Derivative); (1R,2R)-(-)-1,2-Diaminocyclohexane N,N'-bis(3,5-di-tert-butylsalicylidene); (R,R)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine; (R,R)-H2salentBu; Chiral Salen Ligand; 323193-85-7
EINECS	Contact for details

Quality Control

Our production of this chiral ligand adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Each lot is characterized by advanced analytical techniques, including chiral HPLC, NMR, and elemental analysis. Certificates of Analysis (COA) detailing purity, chiral purity, and full spectroscopic data are provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.