Description

6-(Trifluoromethyl)-1H-Indene is a high-value fluorinated indene derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique reactivity of the indene scaffold combined with the electron-withdrawing and lipophilicity-enhancing properties of the trifluoromethyl group. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules for new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the CF3 group for improved bioactivity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on aromatic systems.
• Fine Chemical Synthesis: Intermediate for producing complex fluorinated aromatic compounds used in dyes, pigments, and other high-value chemicals.

Basic Information

Item	Detail
Product Name	6-(Trifluoromethyl)-1H-Indene
CAS No.	321937-10-4
Molecular Formula	C10H7F3
Molecular Weight	184.16 g/mol
Synonyms	6-(Trifluoromethyl)indene; 1H-Indene, 6-(trifluoromethyl)-; 6-Trifluoromethyl-1H-indene; 6-Trifluoromethylindene; 6-CF3-indene; 6-(Trifluoromethyl)indene; (6-Trifluoromethyl-1H-inden-1-yl); Indene, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-1H-Indene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.