Description

2-Phenyl-3'-Trifluoromethylacetophenone is a specialized aromatic ketone derivative characterized by its phenyl and trifluoromethyl substituents. This compound is a high-value intermediate prized for its unique structural motifs that confer desirable properties in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the construction of complex molecules, where the trifluoromethyl group is instrumental in modulating biological activity and physicochemical characteristics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for developing novel organic electronic materials, liquid crystals, and functional polymers.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the introduction and reactivity of the trifluoromethyl group in organic synthesis.

Basic Information

Product Name	2-Phenyl-3'-Trifluoromethylacetophenone
CAS No.	1533-04-6
Molecular Formula	C15H11F3O
Molecular Weight	264.24 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-2-phenylethanone; 3'-Trifluoromethyl-2-phenylacetophenone; 2-Phenyl-1-[3-(trifluoromethyl)phenyl]ethanone; 3-(Trifluoromethyl)desoxybenzoin; α-Phenyl-3'-(trifluoromethyl)acetophenone; 3'-Trifluoromethyldesoxybenzoin; Ethanone, 1-[3-(trifluoromethyl)phenyl]-2-phenyl-
EINECS	Contact for details

Quality Control

Our production of 2-Phenyl-3'-Trifluoromethylacetophenone adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.