Description

1-Fluoro-4-Iodonaphthalene is a halogenated naphthalene derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for applications in cross-coupling reactions and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides due to its reactivity in forming carbon-carbon bonds.
• Material Science Research: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organometallic catalysts.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the effects of fluorine substitution on aromatic systems.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Fluoro-4-Iodonaphthalene
CAS No.	17318-09-1
Molecular Formula	C₁₀H₆FI
Molecular Weight	272.06 g/mol
Synonyms	4-Fluoro-1-iodonaphthalene; 1-Iodo-4-fluoronaphthalene; Naphthalene, 1-fluoro-4-iodo-; 1-Fluoro-4-iodonaphthalene; 4-Fluoro-α-iodonaphthalene; 1-Fluoro-4-iodo-naphthalene; 1-Fluoronaphthalene-4-iodide
EINECS	Contact for details

Quality Control

Our 1-Fluoro-4-Iodonaphthalene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to verify identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to quality ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.