Description

2-Fluoro-2'-Bromobiphenyl is a high-purity halogenated biphenyl derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular structure, which provides two distinct reactive sites for selective functionalization, enabling the construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those with biphenyl-based scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands in catalysis and material science.
• Functional Material Development: Integral to the creation of organic semiconductors, liquid crystals, and photoresists.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form more complex biaryl systems.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in research laboratories.

Basic Information

Product Name	2-Fluoro-2'-Bromobiphenyl
CAS No.	1554-05-8
Molecular Formula	C12H8BrF
Molecular Weight	251.10 g/mol
Synonyms	2-Bromo-2'-fluorobiphenyl; 1-Bromo-2-(2-fluorophenyl)benzene; [1,1'-Biphenyl]-2-bromo-2'-fluoro; 2'-Fluoro-2-bromobiphenyl; Biphenyl, 2-bromo-2'-fluoro-; 2-(2-Bromophenyl)fluorobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-2'-Bromobiphenyl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.