Description

1-Bromo-3-Fluoroisoquinoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique halogenated structure, which provides two distinct reactive sites for selective functionalization, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, ligand synthesis, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold's bioactivity.
• Ligand Synthesis: Serves as a versatile starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes and enzyme activity.
• Cross-Coupling Reactions: Acts as a competent substrate in palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations.

Basic Information

Product Name	1-Bromo-3-Fluoroisoquinoline
CAS No.	1076-36-4
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	3-Fluoro-1-bromoisoquinoline; 1-Bromo-3-fluoroisoquinoline; Isoquinoline, 1-bromo-3-fluoro-; 3-Fluoro-1-bromo-isoquinoline; 1076-36-4; 1-Bromo-3-fluoro-isoquinoline; 1-Bromo-3-fluoro-isoquinoline (ACI); 1-Bromo-3-fluoroisoquinoline, 97%
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoroisoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality assurance ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.