Description

5-Fluoro-1H-Benzimidazole is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated benzimidazole-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and development of new-generation fungicides and herbicides that leverage the fluorobenzimidazole scaffold for improved efficacy.
• Material Science Research: Employed as a building block for creating novel organic electronic materials, ligands, and fluorinated polymers.
• Biochemical Tool Compound: Utilized in life science research to study enzyme inhibition and modulate biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	5-Fluoro-1H-Benzimidazole
CAS No.	1977-72-6
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	5-Fluorobenzimidazole; 5-Fluoro-1H-benzo[d]imidazole; 5-Fluoro-1H-benzimidazole; 1H-Benzimidazole, 5-fluoro-; 5-Fluorobenzimidazole; 5-F-BIM; 5-Fluor-1H-benzimidazol; 5-Fluoro-1H-benzoimidazole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Benzimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.