Description

5,6,7-Trifluoroisatin CAS NO 107583-37-9 is a high-value fluorinated isatin derivative, a crucial advanced intermediate in modern synthetic organic chemistry. Its trifluoromethyl-substituted aromatic core makes it an indispensable building block for constructing complex molecules with enhanced biological activity and metabolic stability. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, including kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Building block for developing new generation pesticides and herbicides with improved efficacy and environmental profile.
• Material Science: Used in the research of organic semiconductors and fluorinated polymers for electronic applications.
• Chemical Synthesis: Versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Bioconjugation & Probe Development: Serves as a reactive handle for labeling and bioconjugation strategies in biochemical research.

Basic Information

Product Name	5,6,7-Trifluoroisatin
CAS No.	107583-37-9
Molecular Formula	C8H2F3NO2
Molecular Weight	209.10 g/mol
Synonyms	5,6,7-Trifluoro-1H-indole-2,3-dione; 5,6,7-Trifluoroindoline-2,3-dione; 1H-Indole-2,3-dione, 5,6,7-trifluoro-; 5,6,7-Trifluoro-2,3-dihydro-1H-indole-2,3-dione; Trifluoroisatin; 5,6,7-Trifluorooxindole
EINECS	Contact for details

Quality Control

Our 5,6,7-Trifluoroisatin is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full spectroscopic data are provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.