Description

4-Fluorogramine is a specialized fluorinated derivative of the gramine alkaloid, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic introduction of a fluorine atom, which can significantly alter the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who are developing novel active ingredients, particularly for applications in medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including potential central nervous system (CNS) agents and receptor modulators.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental persistence.
• Chemical Biology Probe: Serves as a precursor for creating fluorescent or tagged molecular probes to study biological pathways and enzyme functions.
• Organic Synthesis: A versatile reagent for constructing complex indole-based heterocycles, which are privileged scaffolds in medicinal chemistry.
• Material Science Research: Potential monomer or precursor for developing specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	4-Fluorogramine
CAS No.	101909-46-0
Molecular Formula	C12H15FN2
Molecular Weight	206.26 g/mol
Synonyms	1-(3-(Dimethylamino)propyl)-4-fluoro-1H-indole; 4-Fluoro-3-(3-(dimethylamino)propyl)indole; 4-Fluorogramine; 4-Fluoro-N,N-dimethyltryptamine precursor; 4-F-DMT Precursor
EINECS	Contact for details

Quality Control

Our 4-Fluorogramine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC-MS for impurity profiling. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.