Description

(1S 4S)-(-)-2-(4-Methylphenyl)-2 5-Diazabicyclo[2.2.1]heptane is a chiral diazabicyclic compound of significant interest in advanced organic synthesis and pharmaceutical research. Its rigid, three-dimensional bicyclic structure and defined stereochemistry make it a valuable scaffold and chiral building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This product is primarily utilized by R&D chemists and process development scientists in pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex molecular architectures with high stereochemical purity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor or scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets.
• Asymmetric Catalysis Ligand: Used as a precursor for developing novel chiral ligands or organocatalysts to control stereoselectivity in synthetic transformations.
• Agrochemical Research: Employed in the discovery and development of new, stereochemically defined active ingredients for crop protection.
• Academic & Institutional R&D: A valuable tool compound for methodological studies in organic chemistry and medicinal chemistry programs.
• Fine Chemical Synthesis: Acts as a building block for creating complex molecules with specific three-dimensional shapes for material science or specialty chemical applications.

Basic Information

Product Name	(1S 4S)-(-)-2-(4-Methylphenyl)-2 5-Diazabicyclo[2.2.1]heptane
CAS No.	312624-04-7
Molecular Formula	C12H16N2
Molecular Weight	188.27 g/mol
Synonyms	(1S,4S)-2-(p-Tolyl)-2,5-diazabicyclo[2.2.1]heptane; (-)-2-(4-Methylphenyl)-2,5-diazabicyclo[2.2.1]heptane; (1S,4S)-2-(4-Methylphenyl)-2,5-diazabicyclo[2.2.1]heptane; 2,5-Diazabicyclo[2.2.1]heptane, 2-(4-methylphenyl)-, (1S,4S)-; p-Tolyl-DABN derivative; Chiral DABN scaffold
EINECS	Contact for details

Quality Control

Our production of (1S 4S)-(-)-2-(4-Methylphenyl)-2 5-Diazabicyclo[2.2.1]heptane adheres to stringent internal quality standards to ensure batch-to-batch consistency and high stereochemical purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to confirm identity and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.