Description

4-Fluoro-3-(Piperidine-1-Sulfonyl)-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzoic acid core substituted with a fluorine atom and a piperidine sulfonyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Protease Inhibitor Synthesis: Used in the construction of molecules designed to inhibit specific protease enzymes.
• Kinase Inhibitor Development: Serves as a core scaffold for creating potential kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Research: Employed as a tool compound or a labeled probe for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke organic synthesis projects requiring this specific sulfonamide-benzoic acid derivative.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and organofluorine chemistry.

Basic Information

Product Name	4-Fluoro-3-(Piperidine-1-Sulfonyl)-Benzoic Acid
CAS No.	311785-51-0
Molecular Formula	C₁₂H₁₄FNO₄S
Molecular Weight	287.31 g/mol
Synonyms	4-Fluoro-3-(piperidine-1-sulfonyl)benzoic acid; 3-(1-Piperidinosulfonyl)-4-fluorobenzoic Acid; Benzoic acid, 4-fluoro-3-(1-piperidinylsulfonyl)-; 4-Fluoro-3-piperidin-1-ylsulfonyl-benzoic acid; 311785-51-0; 4-Fluoro-3-(piperidin-1-ylsulfonyl)benzoic acid
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-3-(Piperidine-1-Sulfonyl)-Benzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.