Description

(R)-(1-Aminohexyl)Phosphonic Acid CAS NO 308103-42-6 is a chiral, non-proteinogenic amino acid derivative featuring a phosphonic acid group, which serves as a stable bioisostere for phosphate. This compound is a valuable chiral building block and ligand in asymmetric synthesis and medicinal chemistry research. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers for developing novel enzyme inhibitors, metal chelators, and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly enzyme inhibitors targeting metalloenzymes.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral phosphonate ligands used in transition metal-catalyzed asymmetric reactions.
• Biochemical Research: Used as a tool compound in studying enzyme mechanisms, signal transduction pathways, and bone metabolism due to its phosphonate moiety.
• Material Science: Potential monomer or additive for creating functional polymers with specific metal-binding or surface-modifying properties.
• Agrochemical Research: Investigated as a building block for developing new herbicides or plant growth regulators with chiral specificity.

Basic Information

Product Name	(R)-(1-Aminohexyl)Phosphonic Acid
CAS No.	308103-42-6
Molecular Formula	C6H16NO3P
Molecular Weight	181.17 g/mol
Synonyms	(R)-1-Aminohexylphosphonic Acid; (R)-1-Amino-hexyl-phosphonic Acid; (R)-α-Aminocaprylphosphonic Acid; (R)-6-Aminohexylphosphonic Acid; D-1-Aminohexylphosphonic Acid; (R)-HAPA; Phosphonic acid, P-[(1R)-1-aminohexyl]-; (1R)-1-Aminohexylphosphonic Acid
EINECS	Contact for details

Quality Control

Our (R)-(1-Aminohexyl)Phosphonic Acid is produced under a strict quality management system. Each batch is characterized and tested to ensure identity, purity, and chiral integrity, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, Chiral HPLC) and spectroscopic results are provided to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.