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2,2'-(2,5-Difluoro-1,4-Phenylene)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) CAS NO 303006-90-8


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CAS No.:303006-90-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,2'-(2,5-Difluoro-1,4-Phenylene)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) is a high-purity, bifunctional boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Synthesis: Used in the development of novel, fluorinated herbicides, fungicides, and insecticides.
  • Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating fluorinated electron-transport materials and emissive layer components.
  • Polymer Chemistry: Enables the synthesis of specialty fluorinated polymers and conjugated materials for electronic applications.
  • Ligand & Catalyst Development: Utilized to construct complex, fluorinated organic ligands for metal catalysis.
  • Material Science Research: Acts as a versatile monomer for creating novel organic frameworks and advanced functional materials.

Basic Information

Product Name 2,2'-(2,5-Difluoro-1,4-Phenylene)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane)
CAS No. 303006-90-8
Molecular Formula C22H32B2F2O4
Molecular Weight 420.11 g/mol
Synonyms 1,4-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-difluorobenzene; 2,5-Difluoro-1,4-phenylenebis(boronic acid pinacol ester); 2,5-Difluoro-1,4-phenylenebis(pinacolboronate); 2,5-Difluorobenzene-1,4-diboronic acid bis(pinacol ester); 2,5-Difluoro-1,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; 2,5-Difluoro-p-phenylenebis(boronic acid pinacol ester); 303006-90-8; 2,5-Difluoro-1,4-phenylenebis(boronic acid) pinacol ester
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Quality Control

Our 2,2'-(2,5-Difluoro-1,4-Phenylene)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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