Description

Ethyl Bromoacetate, [2-14C] is a carbon-14 labeled isotopologue of ethyl bromoacetate, a versatile alkylating agent and synthetic intermediate. This radiolabeled compound is essential for conducting precise metabolic, pharmacokinetic, and environmental fate studies, providing critical data for regulatory submissions and scientific research. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and life science research sectors who require high-specific-activity tracers for advanced analytical applications.

Application

• Tracer Studies in Pharmaceutical R&D: Used as a radiolabeled precursor for tracking the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities and their metabolites.
• Agrochemical Research: Employed in environmental fate studies to understand the degradation pathways and residue profiles of pesticides and herbicides.
• Biochemical Pathway Analysis: Serves as a tool for elucidating biosynthetic pathways and enzymatic mechanisms in biochemical research.
• Organic Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex carbon-14 labeled target molecules for various research applications.
• Quality Control & Reference Standard: Can be used as an internal standard or reference material in advanced analytical methods like LC-MS for quantification.

Basic Information

Product Name	Ethyl Bromoacetate, [2-14C]
CAS No.	39863-84-8
Molecular Formula	C4H714COOCH2Br
Molecular Weight	~167.00 g/mol (for labeled form)
Synonyms	Bromoacetic-2-14C acid ethyl ester; Ethyl 2-bromoacetate-2-14C; [2-14C]Ethyl bromoacetate; Bromoacetic acid ethyl ester-2-14C; 14C-Ethyl bromoacetate; Ethyl α-bromoacetate-2-14C; Ethyl bromoethanoate-2-14C; NSC 8862-2-14C
EINECS	Contact for details

Quality Control

Every batch of Ethyl Bromoacetate, [2-14C] is produced and analyzed under strict quality systems to ensure high chemical and radiochemical purity, specific activity, and stability. Our products undergo rigorous quality testing, including HPLC, NMR, and radio-TLC analysis, to ensure compliance with research standards. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity, solvent, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a dedicated, well-ventilated area for radioactive materials. Keep away from strong acids and organic solvents. Follow all local and international regulations for the storage and handling of radioactive substances.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (Radio-TLC/HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent	Specified on COA (e.g., Toluene, Acetone)
Concentration	Specified on COA (mCi/mL or mg/mL)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.