Description

Penciclovir CAS NO 39809-25-1 is a potent synthetic acyclic guanine derivative antiviral agent. Its primary value lies in its selective inhibition of viral DNA polymerase, making it a critical active pharmaceutical ingredient (API) for antiviral therapies. This compound is essential for pharmaceutical manufacturers developing and producing antiviral medications targeting herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in topical antiviral creams and ointments for the treatment of herpes labialis (cold sores).
• Antiviral Drug Synthesis: Serves as a key intermediate in the synthesis of more complex antiviral prodrugs, such as Famciclovir.
• Research & Development: Utilized in virology and pharmaceutical R&D for studying antiviral mechanisms and screening new therapeutic candidates.
• Veterinary Pharmaceuticals: Applied in formulations for treating viral infections in animals.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for drug testing and method validation.

Basic Information

Product Name	Penciclovir
CAS No.	39809-25-1
Molecular Formula	C10H15N5O3
Molecular Weight	253.26 g/mol
Synonyms	9-[4-Hydroxy-3-(hydroxymethyl)but-1-yl]guanine; 2-Amino-9-(4-hydroxy-3-hydroxymethylbut-1-yl)-1,9-dihydro-6H-purin-6-one; BRL 39123; Denavir (brand name); PCV; Penciclovirum
EINECS	Contact for details

Quality Control

Our Penciclovir is manufactured under strict quality management systems, targeting purity levels suitable for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing including HPLC assay, related substances analysis, and residual solvent determination to ensure compliance with in-house specifications and relevant pharmacopeial guidelines. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.