Description

Colchicosamide is a specialized alkaloid derivative, recognized for its unique structural and biological properties. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential as a key intermediate or active pharmaceutical ingredient (API). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of novel therapeutic agents and biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex alkaloid-based drugs and investigational new chemical entities.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate cellular mechanisms and biological pathways.
• API Development: Acts as a potential starting material or precursor in the development of new Active Pharmaceutical Ingredients (APIs) targeting specific therapeutic areas.
• Academic & Industrial R&D: Employed in university laboratories and corporate R&D centers for method development, structure-activity relationship (SAR) studies, and process chemistry.
• Standards & Calibration: Utilized to prepare high-purity analytical standards for quality control and regulatory testing in pharmaceutical manufacturing.

Basic Information

Product Name	Colchicosamide
CAS No.	38838-23-2
Molecular Formula	C21H25NO5
Molecular Weight	371.43 g/mol
Synonyms	N-[(7S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; Colchiceinamide; Demecolcine analog; Colchicoside aglycone amide; N-Acetylcolchiceinamide; 3-Demethylcolchicine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Colchicosamide is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling using advanced techniques like HPLC and NMR. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific customer or regulatory requirements, including those for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.