Description

[S,(+)]-4,4A,5,6,7,8-Hexahydronaphthalene-2(3H)-One is a high-purity, chiral organic compound belonging to the class of hexahydronaphthalenones. This specific enantiomer is a critical chiral building block and intermediate in advanced organic synthesis, valued for its defined stereochemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors for the development of active pharmaceutical ingredients (APIs) and complex specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Serves as a versatile starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, agrochemicals, and advanced materials where specific stereochemistry is required.
• Academic & Industrial Research: Employed in methodological development, total synthesis projects, and as a reference standard in analytical chemistry.
• Fragrance & Flavor Chemistry: Potential use as an intermediate for synthesizing specific stereoisomers of odorants and flavor compounds.

Basic Information

Product Name	[S,(+)]-4,4A,5,6,7,8-Hexahydronaphthalene-2(3H)-One
CAS No.	38772-79-1
Molecular Formula	C₁₀H₁₄O
Molecular Weight	150.22 g/mol
Synonyms	(S)-(+)-4,4a,5,6,7,8-Hexahydro-2(3H)-naphthalenone; (S)-(+)-1,2,3,4,4a,5,6,7-Octahydro-2-naphthalenone; (S)-(+)-Octalone; (S)-(+)-α,β-Octalone; (S)-(+)-4,4a,5,6,7,8-Hexahydro-2H-naphthalen-2-one; (S)-4,4a,5,6,7,8-Hexahydronaphthalen-2(3H)-one; (S)-Octalone; (S)-α,β-Octalone
EINECS	Contact for details

Quality Control

Our [S,(+)]-4,4A,5,6,7,8-Hexahydronaphthalene-2(3H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC/GC, to ensure it meets the exacting standards required for synthetic applications. Certificates of Analysis (COA) with full specification data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.