Description

2-Amino-9-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One is a high-purity nucleoside derivative of significant importance in pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel antiviral and anticancer agents. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based therapeutics. Our supply ensures consistent quality and reliable availability for your most demanding R&D and production needs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of advanced nucleoside analogs with potential antiviral or anticancer activity.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic pathway analysis, and molecular biology research.
• Antiviral Drug Development: Serves as a core scaffold for researching new therapeutic agents targeting viral polymerases and replication mechanisms.
• Oncology Research: Investigated for its role in developing prodrugs and targeted therapies that interfere with cancer cell DNA/RNA synthesis.
• Process Chemistry & Scale-Up: Supplied to support route scouting, optimization, and cGMP manufacturing of active pharmaceutical ingredients (APIs).
• Analytical Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical labs.

Basic Information

Item	Details
Product Name	2-Amino-9-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One
CAS No.	38559-49-8
Molecular Formula	C10H13N5O4
Molecular Weight	267.24 g/mol
Synonyms	2-Amino-9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one; 2-Aminoadenosine; Cordycepin intermediate; 9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-amino-1,9-dihydro-6H-purin-6-one; 2-Amino-9-β-D-ribofuranosylpurin-6(1H)-one; 2-Aminoadenosine (incorrect but common alias); 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purin-6-one
EINECS	Contact for details

Quality Control

Our 2-Amino-9-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-3H-Purin-6-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.