Description

1-α-H,5-α-H-Tropan-3-α-Ol, 2,2-Diphenyl-3-Hydroxypropionat E is a specialized tropane alkaloid derivative, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its precise stereochemistry and functional groups, which are critical for producing active pharmaceutical ingredients (APIs) with specific pharmacological profiles. It is primarily required by research institutions and manufacturers in the pharmaceutical industry developing neurological and therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex tropane-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical and research settings for developing compounds that interact with cholinergic and other neurological pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of specialty medicines.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships of alkaloid derivatives.

Basic Information

Product Name	1-α-H,5-α-H-Tropan-3-α-Ol, 2,2-Diphenyl-3-Hydroxypropionat E
CAS No.	38545-48-1
Molecular Formula	C24H27NO3
Molecular Weight	377.48 g/mol
Synonyms	3α-Hydroxytropane 2,2-diphenylpropionate; Tropine 2,2-diphenylpropionate; 3α-Tropanyl 2,2-diphenylpropionate; 1αH,5αH-Tropan-3α-ol 2,2-diphenylpropanoate; (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2,2-diphenylpropanoate; Tropine diphenylpropionate; Ester of tropine and 2,2-diphenylpropionic acid
EINECS	Contact for details

Quality Control

Our 1-α-H,5-α-H-Tropan-3-α-Ol, 2,2-Diphenyl-3-Hydroxypropionat E is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.