Description

Hemoglobin Sabine is a specialized, naturally occurring hemoglobin variant with the CAS registry number 37251-39-1, distinguished by its unique oxygen-binding properties. This high-purity biochemical is critical for advanced research and development in life sciences, where precise and reliable materials are paramount. It serves as an essential reagent for scientists and manufacturers in the pharmaceutical, diagnostic, and biomedical research sectors, enabling groundbreaking work in hematology, oxygen therapeutics, and biochemical assays.

Application

• Biochemical Research & Standard Development: Used as a reference standard and key reagent in studies of hemoglobin function, oxygen transport kinetics, and protein structure-activity relationships.
• Diagnostic Kit Manufacturing: Incorporated as a critical component in the calibration and formulation of clinical diagnostic kits for blood disorders and hematological analysis.
• Pharmaceutical R&D: Employed in the research and development of novel oxygen-carrying therapeutics, blood substitutes, and targeted drug delivery systems.
• Academic & Clinical Laboratories: Serves as a vital tool for teaching and investigative procedures in university and hospital laboratory settings.
• Biotechnology Processes: Utilized in enzymatic assays and as a model protein in bioprocessing and purification technique development.

Basic Information

Product Name	Hemoglobin Sabine
CAS No.	37251-39-1
Molecular Formula	C738H1166N203O208S2Fe (Typical for hemoglobin tetramer)
Molecular Weight	~64,500 Da (Approximate, for α2β2 tetramer)
Synonyms	Hb Sabine; Hemoglobin variant Sabine; Unstable hemoglobin Sabine; Hemoglobin β 91(F7) Leu→Pro; HBB: c.274T>C; Hemoglobin Sabine (human); Oxyhemoglobin Sabine; Methemoglobin Sabine
EINECS	Contact for details

Quality Control

Every batch of Hemoglobin Sabine CAS 37251-39-1 is manufactured and controlled under stringent quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity, electrophoresis for variant confirmation, and spectrophotometry for functional assessment, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, potency, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below under an inert atmosphere. This product is light-sensitive and easily oxidized; avoid repeated freeze-thaw cycles and prolonged exposure to air. Aliquot contents upon receipt to minimize degradation.

Specification

Item	Specification
Appearance	Dark red to brown lyophilized powder or solution
Identification (HPLC/Electrophoresis)	Conforms to Hemoglobin Sabine standard
Purity (HPLC)	≥ 95% (by area)
Assay (Spectrophotometric)	90% - 110% of labeled concentration
Methemoglobin Content	< 5%
Solubility	Clear solution in buffer or water at specified concentration
Endotoxin	< 1.0 EU/mg (for applicable grades)
Biological Activity (O2 Binding)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.