Description

Aniline Hydrochloride, [14C(U)] is a carbon-14 radiolabeled derivative of aniline hydrochloride, a key aromatic amine salt. This isotopically labeled compound is essential for conducting advanced metabolic, pharmacokinetic, and environmental fate studies, providing critical traceability in research. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical companies, and academic institutions engaged in sophisticated tracer analysis and mechanistic investigations.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a radiolabeled tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of aniline-containing drug candidates.
• Environmental Fate and Ecotoxicology Research: Enables precise tracking of aniline derivatives and their degradation products in environmental systems to assess persistence and bioaccumulation.
• Biochemical Pathway Elucidation: Serves as a tool for tracing metabolic pathways in biological systems, helping to identify metabolites and understand biotransformation mechanisms.
• Agrochemical Research: Employed in studies to determine the metabolic breakdown and environmental impact of aniline-based herbicides and pesticides.
• Chemical Synthesis Intermediary: Acts as a labeled building block for the synthesis of more complex carbon-14 labeled compounds for research purposes.
• Analytical Method Development: Used as a standard or reference material in developing and validating sensitive analytical methods like LC-MS/MS for aniline detection.

Basic Information

Product Name	Aniline Hydrochloride, [14C(U)]
CAS No.	36663-09-9
Molecular Formula	C6H7N • HCl (with uniform 14C labeling in the phenyl ring)
Molecular Weight	129.59 g/mol (unlabeled); Specific activity provided on COA.
Synonyms	Aniline Hydrochloride-14C(U); Benzenamine Hydrochloride-14C(U); Phenylamine Hydrochloride-14C(U); Aniline Chloride-14C; Aniline HCl-14C; [U-14C]Aniline Hydrochloride; Aniline Hydrochloride (phenyl-14C); Anilinium Chloride-14C
EINECS	Contact for details

Quality Control

Every batch of Aniline Hydrochloride, [14C(U)] is produced and analyzed under strict quality protocols to ensure high chemical, radiochemical, and isotopic purity suitable for advanced research. Certificates of Analysis (COA) are provided, detailing key parameters such as specific activity, radiochemical purity (typically by HPLC), chemical purity, and solvent content. Our quality system is designed to support GLP-compliant research and ensure reliable, reproducible results in sensitive tracer applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage of solutions, consider conditions appropriate for radiolabeled compounds. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customizable; mCi/mmol range (see COA)
Solvent Content (Residual Solvents)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.