Description

n-Butylamine-1-14C Hydrochloride is a carbon-14 labeled salt of n-butylamine, a critical tool compound for metabolic and pharmacokinetic studies in research and development. This radiolabeled derivative is essential for tracing the fate of butylamine-containing molecules within biological systems, providing invaluable data on absorption, distribution, metabolism, and excretion (ADME). It is primarily utilized by pharmaceutical, agrochemical, and environmental research organizations requiring precise analytical tracking for regulatory submissions and mechanistic investigations.

Application

• ADME (Absorption, Distribution, Metabolism, Excretion) Studies: Used as a radiotracer to investigate the metabolic pathways and pharmacokinetic profile of butylamine-based compounds in preclinical research.
• Pharmaceutical R&D: Serves as a key intermediate or tracer in the development of new active pharmaceutical ingredients (APIs) where understanding butylamine moiety metabolism is crucial.
• Agrochemical Research: Employed in environmental fate studies to track the degradation, metabolism, and residue profile of pesticides or herbicides containing butylamine structures.
• Biochemical Pathway Analysis: Facilitates the elucidation of specific enzymatic reactions and biochemical transformations involving primary amines in metabolic networks.
• Analytical Method Development: Acts as an internal standard or reference material in advanced analytical techniques like LC-MS (Liquid Chromatography-Mass Spectrometry) for quantitative bioanalysis.
• Regulatory Safety Testing: Supports toxicology and safety assessment studies required for product registration with agencies such as the FDA and EMA.

Basic Information

Product Name	n-Butylamine-1-14C Hydrochloride
CAS No.	36559-70-3
Molecular Formula	C4H12ClN * (14C)
Molecular Weight	Contact for details
Synonyms	1-Aminobutane-1-14C Hydrochloride; Butylamine-1-14C Hydrochloride; n-Butanamine-1-14C Hydrochloride; 14C-Butylamine Hydrochloride; [1-14C]-Butylamine Hydrochloride; 1-Butylamine-1-14C Hydrochloride; Butan-1-amine-1-14C hydrochloride; (1-14C)Butylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of n-Butylamine-1-14C Hydrochloride is manufactured and analyzed under strict quality control protocols to ensure high chemical, radiochemical, and isotopic purity suitable for sensitive research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific radioactivity, purity by HPLC, and identification are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at recommended temperatures (typically 2-8°C or as specified on the label). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under inert atmosphere if specified. Store in accordance with all local and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (Chemical Purity)
Radiochemical Purity	≥ 97%
Specific Radioactivity	Contact for details (mCi/mmol)
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.