Description

(4S)-4β,5β-Dimethyl-1,3-Dioxolane-2-One CAS NO 36368-39-5 is a high-purity, chiral cyclic carbonate derivative, specifically the (4S)-enantiomer of 4,5-dimethyl-1,3-dioxolan-2-one. This compound serves as a versatile chiral building block and intermediate in advanced organic synthesis, enabling the introduction of stereochemistry into target molecules. It is primarily needed by pharmaceutical, agrochemical, and specialty chemical R&D and production teams for the development of enantiomerically pure active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in nucleoside and carbocyclic analog development.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective reactions to control absolute configuration.
• Agrochemicals: Building block for creating chiral active ingredients in herbicides, fungicides, and insecticides with improved efficacy and environmental profile.
• Ligand and Catalyst Preparation: Precursor for synthesizing chiral ligands used in asymmetric catalysis (e.g., hydrogenation, epoxidation).
• Polymer Science: Monomer for the production of chiral or functionalized polycarbonates and polyesters with specialized properties.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex natural products, flavors, and fragrances.
• Academic & Industrial R&D: Valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(4S)-4β,5β-Dimethyl-1,3-Dioxolane-2-One
CAS No.	36368-39-5
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	(4S)-(-)-4,5-Dimethyl-1,3-dioxolan-2-one; (S)-(-)-4,5-Dimethyl-1,3-dioxolan-2-one; (4S)-4,5-Dimethyl-2-oxo-1,3-dioxolane; L-4,5-Dimethyl-1,3-dioxolan-2-one; (S)-4,5-Dimethyl-1,3-dioxolane-2-one; (4S)-cis-4,5-Dimethyl-1,3-dioxolan-2-one; Chiral dimethyl ethylene carbonate
EINECS	Contact for details

Quality Control

Our (4S)-4β,5β-Dimethyl-1,3-Dioxolane-2-One is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the exacting standards required for chiral intermediates. Certificates of Analysis (COA) detailing identity, assay, chiral purity (enantiomeric excess), and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.