Description

Diisopropyl Phenylphosphonite is a versatile organophosphorus compound widely used as a key intermediate and ligand in organic synthesis. Its primary value lies in its role as a highly effective reagent for the formation of phosphorus-carbon bonds and as a catalyst component in various cross-coupling and polymerization reactions. This chemical is essential for R&D and production within the pharmaceutical, agrochemical, and specialty polymer industries, where precise molecular construction is critical.

Application

• As a crucial ligand and catalyst precursor in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi).
• As a key phosphitylating agent in the synthesis of nucleotide analogs and oligonucleotides for pharmaceutical research.
• In the production of flame retardants and specialty phosphorus-containing polymers.
• As an intermediate in the manufacture of agrochemicals, including certain herbicides and plant growth regulators.
• For the stabilization of polymers against thermal and oxidative degradation.
• In organic synthesis laboratories for the preparation of phosphonates and phosphinates, valuable building blocks in medicinal chemistry.

Basic Information

Product Name	Diisopropyl Phenylphosphonite
CAS No.	36238-99-0
Molecular Formula	C12H19O2P
Molecular Weight	226.25 g/mol
Synonyms	Phenylphosphonic Acid Diisopropyl Ester; Diisopropyl Phenylphosphonate; P,P-Diisopropyl P-Phenylphosphonite; Phosphonous Acid, Phenyl-, Diisopropyl Ester; Isopropyl Phenylphosphonite; Phenyl Diisopropylphosphonite; (Isopropoxy)(phenyl)phosphine; Diisopropyl Phenyl Phosphonite
EINECS	Contact for details

Quality Control

Our Diisopropyl Phenylphosphonite is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards demanded by the fine chemical and pharmaceutical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C to maximize stability. This material is hygroscopic and easily oxidized; containers must be kept sealed and handled under inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC or NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.