Description

Butriptyline is a tricyclic antidepressant (TCA) compound of significant interest in pharmaceutical research and development. Its primary value lies in its role as a reference standard and active pharmaceutical ingredient (API) for analytical and formulation studies. This product is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in neuropharmacology research, method development, and quality control processes. We supply high-purity Butriptyline CAS NO 35941-65-2 to support critical work in drug discovery and regulatory compliance.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, GC-MS) and the validation of testing methods in quality control laboratories.
• Active Pharmaceutical Ingredient (API): Serves as the core component in the research and development of antidepressant formulations.
• Biochemical Research: Employed in preclinical studies to investigate the mechanisms of action, pharmacokinetics, and metabolism of tricyclic antidepressants.
• Impurity Profiling: Acts as a key marker in the identification and quantification of related substances and degradation products in drug substances and products.
• Academic & Clinical Research: Utilized in university and institutional labs for pharmacological studies and educational purposes.

Basic Information

Product Name	Butriptyline
CAS No.	35941-65-2
Molecular Formula	C21H27N
Molecular Weight	293.45 g/mol
Synonyms	10,11-Dihydro-N,N,β-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine; Butriptyline Hydrochloride (salt form); Evadyne; Evadene; 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; AY-62014; NSC-108164
EINECS	Contact for details

Quality Control

Our Butriptyline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet the stringent requirements for pharmaceutical reference materials. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.