Description

(S)-(-)-2-Methylbutylamine is a chiral, non-racemic primary amine characterized by its high volatility and strong basicity. This optically active building block is essential for introducing a specific stereochemistry into target molecules, enabling the synthesis of enantiomerically pure compounds. It is a critical intermediate for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemical control is paramount for product efficacy and safety.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and fungicides to enhance biological activity and reduce environmental impact.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands and auxiliaries in metal-catalyzed asymmetric synthesis and hydrogenation reactions.
• Flavor and Fragrance Industry: Employed in the synthesis of high-value chiral flavor compounds and aroma chemicals.
• Advanced Material Research: Utilized in the development of chiral liquid crystals, polymers, and other functional materials with specific optical properties.
• Chemical Resolution Agent: Acts as a resolving agent for the separation of racemic mixtures of carboxylic acids and other acidic compounds.

Basic Information

Product Name	(S)-(-)-2-Methylbutylamine
CAS No.	34985-37-0
Molecular Formula	C5H13N
Molecular Weight	87.16 g/mol
Synonyms	(S)-2-Methyl-1-butanamine; (S)-(-)-2-Methylbutylamine; (S)-2-Methylbutan-1-amine; L-2-Methylbutylamine; (S)-1-Amino-2-methylbutane; (2S)-2-Methylbutan-1-amine; (S)-sec-Butylcarbylamine
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-Methylbutylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure compliance with exacting standards for optical purity and chemical identity. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess (ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong oxidizing agents and acids. Due to its high volatility and hygroscopic nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain product integrity. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]20/D	-8.0° to -10.0° (c=1 in EtOH)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.