Description

Bupropion is a synthetic cathinone derivative and a well-established active pharmaceutical ingredient (API) primarily used as an atypical antidepressant and smoking cessation aid. Its core value proposition lies in its unique mechanism of action as a norepinephrine-dopamine reuptake inhibitor (NDRI), which distinguishes it from other major classes of antidepressants. This product is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of antidepressant and anti-addiction medications. We supply high-purity Bupropion CAS NO 34911-55-2 to meet the stringent demands of global pharmaceutical supply chains.

Application

• Pharmaceutical API: Primary use as the active ingredient in antidepressant medications (e.g., Wellbutrin, Zyban).
• Smoking Cessation Therapy: Key component in formulations designed to reduce nicotine cravings and withdrawal symptoms.
• Research & Development: Used in preclinical and clinical studies for investigating neurological pathways and new therapeutic applications.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of branded antidepressant drugs.
• Chemical Intermediate: Serves as a starting material or intermediate in the synthesis of more complex pharmaceutical compounds.
• Reference Standard: High-purity material for use as a calibration standard in analytical laboratories for quality control testing.

Basic Information

Product Name	Bupropion
CAS No.	34911-55-2
Molecular Formula	C13H18ClNO
Molecular Weight	239.74 g/mol
Synonyms	Amfebutamone; (±)-Bupropion; BW 323U; Wellbutrin; Zyban; 2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-one; 1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-
EINECS	Contact for details

Quality Control

Our Bupropion is manufactured and tested under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant Good Manufacturing Practice (GMP) guidelines and can support compliance with major pharmacopoeial standards (e.g., USP, EP) upon request. Our rigorous quality testing ensures batch-to-batch consistency and reliability for your critical formulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.15% Total impurities: ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.