Description

(R)-3,4-Dihydro-8-Hydroxy-3-Methyl-1-Oxo-1H-2-Benzopyran-7-Carboxylic Acid is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the development of optically active pharmaceutical compounds and fine chemicals. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Asymmetric Synthesis: Used as a starting material or reagent in asymmetric catalytic reactions to construct complex molecules with high enantiomeric purity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
• Agrochemical Research: Employed in the research and development of new chiral pesticides and herbicides.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry and process development within research laboratories.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in regulatory and analytical laboratories.

Basic Information

Product Name	(R)-3,4-Dihydro-8-Hydroxy-3-Methyl-1-Oxo-1H-2-Benzopyran-7-Carboxylic Acid
CAS No.	34892-10-9
Molecular Formula	C11H10O5
Molecular Weight	222.19 g/mol
Synonyms	(R)-8-Hydroxy-3-methyl-1-oxo-1H-isochromene-7-carboxylic acid; (R)-3-Methyl-8-hydroxy-1-oxo-1H-2-benzopyran-7-carboxylic acid; (R)-3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-carboxylic acid; (R)-Hymecromone-7-carboxylic acid; (R)-4-Methylumbelliferone-7-carboxylic acid; (R)-7-Carboxy-8-hydroxy-3-methylcoumarin; (R)-3-Methyl-7-carboxy-8-hydroxycoumarin; (R)-3-Methyl-8-hydroxycoumarin-7-carboxylic acid
EINECS	Contact for details

Quality Control

Our (R)-3,4-Dihydro-8-Hydroxy-3-Methyl-1-Oxo-1H-2-Benzopyran-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.