Description

2-Aziridinecarboxylic Acid, 1,3-Dimethyl-, Methyl Ester, (2R,3S)-Rel- (9Ci) CAS NO 34856-91-2 is a high-purity, stereochemically defined aziridine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a constrained, nitrogen-containing three-membered ring system that can be selectively opened to introduce functionalized amine motifs. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where stereochemical control is paramount for biological activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex drug candidates, including protease inhibitors and other biologically active molecules requiring precise stereochemistry.
• Agrochemical Research: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Used to introduce reactive aziridine groups into polymer backbones for cross-linking or to impart specific chemical functionality.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme mechanisms and protein interactions.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and exploring new reaction pathways involving strained heterocycles.

Basic Information

Product Name	2-Aziridinecarboxylic Acid, 1,3-Dimethyl-, Methyl Ester, (2R,3S)-Rel- (9Ci)
CAS No.	34856-91-2
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	Methyl (2R,3S)-1,3-dimethylaziridine-2-carboxylate; rel-(2R,3S)-1,3-Dimethylaziridine-2-carboxylic acid methyl ester; Methyl 1,3-dimethylaziridine-2-carboxylate; Aziridine-2-carboxylic acid, 1,3-dimethyl-, methyl ester, (2R,3S)-rel-; 1,3-Dimethylaziridine-2-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 2-Aziridinecarboxylic Acid, 1,3-Dimethyl-, Methyl Ester, (2R,3S)-Rel- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity assessment. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This compound should be handled and stored under an inert atmosphere to maximize stability and shelf-life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.