Description

Bupropion is a synthetic cathinone derivative and a well-established active pharmaceutical ingredient (API) primarily used as an atypical antidepressant and smoking cessation aid. Its core value lies in its unique mechanism of action as a norepinephrine-dopamine reuptake inhibitor (NDRI), which distinguishes it from other major classes of antidepressants. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for major depressive disorder and nicotine dependence. We supply high-purity Bupropion CAS NO 34841-39-9 to meet the stringent requirements of global pharmaceutical production and advanced clinical research.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of antidepressant and smoking cessation medications.
• Generic Drug Manufacturing: Sourcing for the production of generic versions of Wellbutrin®, Zyban®, and other branded formulations.
• Clinical Research & Development: Utilization in preclinical and clinical studies for new therapeutic applications or novel delivery systems.
• Reference Standard: Serves as a high-purity chemical standard for quality control and analytical testing in laboratories.
• Pharmaceutical Intermediates: Potential use as a key intermediate in the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Bupropion
CAS No.	34841-39-9
Molecular Formula	C13H18ClNO
Molecular Weight	239.74 g/mol
Synonyms	Amfebutamone; (±)-Bupropion; BW 323U; Wellbutrin; Zyban; 2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-one; 1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-
EINECS	Contact for details

Quality Control

Our Bupropion is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC, IR spectroscopy, and residual solvent analysis. We provide full traceability and support regulatory submissions. Certificates of Analysis (COA) are available upon request, detailing compliance with relevant pharmacopeial standards (e.g., USP, EP) and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.15% Total impurities: ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.