Description

Ethyl Bromoacetate, [1-14C] is a carbon-14 labeled isotopologue of ethyl bromoacetate, a versatile alkylating agent and synthetic intermediate. This radiolabeled compound is essential for conducting precise metabolic, pharmacokinetic, and environmental fate studies, providing critical data for regulatory submissions and scientific research. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and life science sectors for tracer applications and mechanistic investigations.

Application

• Tracer Studies in Pharmaceutical R&D: Used to track the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities and drug candidates.
• Agrochemical Research: Employed in environmental fate studies to understand the degradation pathways and metabolite profiles of pesticides and herbicides.
• Biochemical Pathway Analysis: Serves as a labeled precursor for synthesizing more complex radiolabeled molecules to elucidate biosynthetic routes.
• Organic Synthesis Intermediate: Acts as a building block for the preparation of other carbon-14 labeled fine chemicals, peptides, and heterocycles.
• Metabolite Identification: Crucial for identifying and quantifying metabolites in complex biological matrices during drug development.
• Quality Control & Reference Standard: Can be used as an internal standard in advanced analytical methods like LC-MS for accurate quantification.

Basic Information

Product Name	Ethyl Bromoacetate, [1-14C]
CAS No.	34642-38-1
Molecular Formula	C4H714COOCH2Br
Molecular Weight	167.00 g/mol (for unlabeled); Contact for specific activity
Synonyms	Bromoacetic-1-14C acid ethyl ester; Ethyl (1-14C)bromoacetate; [1-14C]Ethyl bromoacetate; Bromoacetic acid ethyl ester-1-14C; Ethyl α-bromoacetate-1-14C; 14C-Ethyl bromoacetate; Carbon-14 labeled ethyl bromoacetate
EINECS	Contact for details

Quality Control

Every batch of Ethyl Bromoacetate, [1-14C] is manufactured and analyzed under strict quality systems to ensure high chemical, radiochemical, and isotopic purity. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards for radiolabeled compounds. Certificates of Analysis (COA) detailing specific activity, purity, and solvent composition are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended cold temperature (e.g., 2-8°C or as specified on the label) to maintain stability. Due to its highly volatile nature, ensure containers are securely sealed and stored in a well-ventilated area, away from strong acids and organic solvents. Handle in accordance with all local, national, and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent	Specified on COA (e.g., Toluene, Acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.