Description

(1R,2S,5R)-(-)-Menthyl Amine is a chiral amine derivative of menthol, characterized by its specific stereochemistry which imparts unique optical activity. This compound is a valuable chiral building block and resolving agent in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and fragrance industries where precise stereochemical control is critical.

Application

• Chiral Auxiliary/Resolving Agent: Used in the asymmetric synthesis of active pharmaceutical ingredients (APIs) to control stereochemistry and produce single enantiomers.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of various therapeutic agents, including antivirals and cardiovascular drugs.
• Catalyst Ligand Synthesis: Employed in the preparation of chiral ligands for transition metal catalysts used in enantioselective reactions.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Flavor and Fragrance Ingredient: Acts as an intermediate for synthesizing high-value aroma chemicals with specific sensory profiles.
• Academic and R&D: A critical reagent in organic chemistry research for developing new synthetic methodologies.

Basic Information

Product Name	(1R,2S,5R)-(-)-Menthyl Amine
CAS No.	34048-57-2
Molecular Formula	C10H21N
Molecular Weight	155.28 g/mol
Synonyms	(-)-Menthylamine; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexylamine; L-Menthylamine; (1R,2S,5R)-(-)-2-Isopropyl-5-methylcyclohexanamine; (1R,2S,5R)-Menthylamine; (-)-1-Methyl-2-(1-methylethyl)cyclohexylamine; (1R,2S,5R)-2-(1-Methylethyl)-5-methylcyclohexanamine
EINECS	Contact for details

Quality Control

Our (1R,2S,5R)-(-)-Menthyl Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC or GC, to ensure compliance with customer specifications and high industry standards. Certificates of Analysis (COA) detailing identity, purity, and specific rotation are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Specific Rotation [α]D20	-20° to -24° (c=1 in Ethanol)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.