Description

Diethyl Pyrocarbonate-Carbonyl-14C is a radiolabeled derivative of diethyl pyrocarbonate (DEPC), a versatile chemical reagent. This compound is specifically designed for research and development applications where carbon-14 tracing is required, offering critical insights into reaction mechanisms, metabolic pathways, and material fate. It is an essential tool for scientists in pharmaceutical development, agrochemical research, and biochemical studies who require precise tracking of carbon atoms.

Application

• Tracer Studies in Pharmaceutical R&D: Used to label and track the metabolic fate, absorption, distribution, and excretion (ADME) of new drug candidates.
• Biochemical Pathway Analysis: Employed in enzymatic and metabolic studies to elucidate carbon flow and identify intermediate compounds.
• Agrochemical Research: Facilitates the study of pesticide and herbicide degradation, environmental persistence, and plant uptake mechanisms.
• Chemical Synthesis Mechanism Investigation: Acts as a radiolabeled reagent to trace reaction pathways and identify byproducts in complex organic syntheses.
• Protein Modification Studies: Utilized to investigate the reaction of DEPC with histidine residues and other nucleophilic sites in proteins, with traceable carbon-14.
• Material Science Research: Applied in polymer and material synthesis to study incorporation rates and the stability of specific chemical linkages.

Basic Information

Product Name	Diethyl Pyrocarbonate-Carbonyl-14C
CAS No.	34037-25-7
Molecular Formula	C6H1014CO5 *
Molecular Weight	~166.1 g/mol (for unlabeled DEPC) *
Synonyms	DEPC-Carbonyl-14C
Diethyl Dicarbonate-Carbonyl-14C
Ethoxyformic Anhydride-Carbonyl-14C
Diethyl Oxydiformate-Carbonyl-14C
Pyrocarbonic Acid Diethyl Ester-Carbonyl-14C
DEPC-14C
Baycovin (labeled derivative)
EINECS	Contact for details

* Note: The exact molecular weight depends on the specific activity and position of the 14C label. Contact us for the exact specification of your batch.

Quality Control

Every batch of Diethyl Pyrocarbonate-Carbonyl-14C is produced and analyzed under strict quality protocols to ensure radiochemical purity, chemical purity, and specific activity meet the exacting standards required for research. Certificates of Analysis (COA) are provided, detailing results from HPLC, radio-HPLC, NMR, and mass spectrometry analyses. Our quality management system supports compliance with relevant GLP (Good Laboratory Practice) guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a dedicated, well-ventilated area for radioactive materials. This compound is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified to maintain stability and specific activity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	Customizable (mCi/mmol)
Solvent	Typically supplied in anhydrous toluene or acetonitrile
Concentration	1.0 mCi/mL (or as customized)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.