Description

Auranofin is a gold-containing organometallic compound primarily known for its potent anti-inflammatory and anti-arthritic properties. Its unique mechanism of action, involving the inhibition of thioredoxin reductase, has made it a compound of significant interest in pharmaceutical research and development. This product is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on developing novel therapeutics for rheumatoid arthritis, cancer, and infectious diseases. Auranofin CAS NO 34031-32-8 represents a high-value active pharmaceutical ingredient (API) and research chemical for advanced medical applications.

Application

• Pharmaceutical API: Serves as the active ingredient in the formulation of anti-arthritic medications.
• Biomedical Research: Used as a critical tool compound in studies investigating inflammation, oxidative stress, and apoptosis pathways.
• Oncology Research: Investigated for its anti-proliferative and pro-apoptotic effects in various cancer cell lines and preclinical models.
• Infectious Disease Research: Studied for its antimicrobial and anti-parasitic activities against pathogens like bacteria and protozoa.
• Chemical Biology: Employed as a selective inhibitor to study the function of selenoproteins and redox regulation in biological systems.
• Reference Standard: Used in analytical laboratories for quality control and method development via HPLC or LC-MS.

Basic Information

Product Name	Auranofin
CAS No.	34031-32-8
Molecular Formula	C20H34AuO9PS
Molecular Weight	678.49 g/mol
Synonyms	(2,3,4,6-Tetra-O-acetyl-1-thio-β-D-glucopyranosato)(triethylphosphine)gold; Ridaura; SKF 39162; AF; Triethylphosphine gold(I) tetraacetylthioglucose; Au(I) triethylphosphine 2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside; Gold triethylphosphine(1+) 2,3,4,6-tetra-O-acetyl-1-thio-β-D-glucopyranoside
EINECS	251-791-8

Quality Control

Our Auranofin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical use. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material that meets specifications for use as a pharmaceutical reference standard or advanced intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.