Description

(3As,7As)-(+)-Hexahydro-3A-Hydroxy-7A-Methyl-1,5-Indandione is a high-purity, chiral indandione derivative with a defined stereochemistry. This compound serves as a critical advanced intermediate in the synthesis of complex pharmaceutical molecules and fine chemicals, where its specific stereocenter is essential for biological activity. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel therapeutic agents, particularly in steroid-like or complex cyclic molecule research.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to construct molecules with high enantiomeric purity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require specific stereochemical configurations.
• Agrochemical Research: Serves as a precursor in the development of new, more effective pesticides and herbicides with targeted modes of action.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development for scale-up.

Basic Information

Product Name	(3As,7As)-(+)-Hexahydro-3A-Hydroxy-7A-Methyl-1,5-Indandione
CAS No.	33879-04-8
Molecular Formula	C10H14O3
Molecular Weight	182.22 g/mol
Synonyms	(+)-Hexahydro-3a-hydroxy-7a-methyl-1,5-indandione; (3aR,7aS)-Hexahydro-3a-hydroxy-7a-methyl-1H-indene-1,5(4H)-dione; 3a-Hydroxy-7a-methyl-perhydroindane-1,5-dione; (3aS,7aS)-3a-Hydroxy-7a-methyloctahydro-1H-indene-1,5-dione; (+)-3a-Hydroxy-7a-methyl-1,5-indandione; 33879-04-8; LK-000031
EINECS	Contact for details

Quality Control

Our (3As,7As)-(+)-Hexahydro-3A-Hydroxy-7A-Methyl-1,5-Indandione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.