Description

(S)-(+)-2-Decanol CAS NO 33758-16-6 is a high-purity chiral secondary alcohol, specifically the (S)-enantiomer of 2-decanol, valued for its role as a versatile chiral building block and resolving agent in asymmetric synthesis. Its defined stereochemistry is critical for producing enantiomerically pure intermediates in pharmaceuticals and fine chemicals, where optical purity directly impacts biological activity and process efficiency. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop or scale up stereoselective syntheses.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used in the production of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or metabolic pathways.
• Asymmetric Catalyst and Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and auxiliaries used in metal-catalyzed asymmetric reactions.
• Chiral Resolving Agent: Employed for the kinetic resolution of racemic mixtures of acids, amines, or other alcohols via esterification or other derivatization techniques.
• Fragrance and Flavor Intermediate: Utilized in the synthesis of high-value chiral aroma chemicals where the specific stereoisomer defines the scent profile.
• Agrochemical Synthesis: Acts as a key chiral synthon in the manufacture of certain herbicides and pesticides with stereospecific activity.
• Research & Development: A standard reagent in academic and industrial laboratories for method development in stereochemistry and organic synthesis.
• Liquid Crystal and Advanced Material Precursor: Used in the synthesis of chiral dopants for liquid crystal displays (LCDs) and other functional organic materials.

Basic Information

Product Name	(S)-(+)-2-Decanol
CAS No.	33758-16-6
Molecular Formula	C10H22O
Molecular Weight	158.28 g/mol
Synonyms	(S)-2-Decanol; (S)-(+)-2-Decanol; (S)-2-Hydroxydecane; (+)-(S)-2-Decanol; (2S)-Decan-2-ol; D-2-Decanol; (S)-Decan-2-ol; sec-Decyl alcohol, (S)-form
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Decanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, assay, enantiomeric excess (ee), and purity is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Optical Rotation [α]D20	+10.0° to +12.0° (c=1 in CHCl3)
Refractive Index nD20	1.435 - 1.439
Density (g/mL, 20°C)	0.825 - 0.835
Water Content (KF)	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.