Description

6,8-Dioxabicyclo[3.2.1]oct-3-en-2-one, (1R,5R)- is a chiral bicyclic lactone compound with the CAS number 33647-85-7. This molecule serves as a valuable and versatile chiral building block in advanced organic synthesis, prized for its rigid, functionalized structure. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring complex, stereodefined ring systems.
• Asymmetric Synthesis: Utilized as a precursor or template in catalytic asymmetric reactions to introduce specific stereochemistry into target molecules.
• Natural Product Synthesis: Serves as a core structural motif or intermediate in the total synthesis of natural products containing fused oxygen heterocycles.
• Ligand and Catalyst Development: Used to construct novel chiral ligands and organocatalysts for enantioselective transformations.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers with unique thermal or optical properties.
• Agrochemical Research: Employed in the research and development of novel, stereochemically defined agrochemicals.

Basic Information

Product Name	6,8-Dioxabicyclo[3.2.1]oct-3-en-2-one, (1R,5R)-
CAS No.	33647-85-7
Molecular Formula	C7H8O3
Molecular Weight	140.14 g/mol
Synonyms	(1R,5R)-6,8-Dioxabicyclo[3.2.1]oct-3-en-2-one; (1R,5R)-(-)-6,8-Dioxabicyclo[3.2.1]oct-3-en-2-one; (1R,5R)-Bicyclic Lactone; (1R,5R)-3,6-Epoxy-2H-pyran-2-one; (1R,5R)-3,6-Epoxy-2-pyrone; Chiral Bicyclic Lactone; (1R,5R)-Enantiomer of 33647-85-7
EINECS	Contact for details

Quality Control

Our 6,8-Dioxabicyclo[3.2.1]oct-3-en-2-one, (1R,5R)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.