Description

(S)-3-Fluoro-1,2-Propanediol is a chiral fluorinated building block of significant interest in advanced organic synthesis. This compound matters because the introduction of fluorine atoms and the defined stereochemistry can dramatically alter the biological activity, metabolic stability, and physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by fine chemical manufacturers producing specialized intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of fluorinated drug candidates, including potential antiviral, anticancer, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorinated Material Science: An intermediate in the synthesis of specialty polymers, surfactants, or liquid crystals where fluorine imparts unique surface properties and chemical resistance.
• Bioconjugation and Probe Chemistry: Useful for introducing a fluorinated, functionalized handle into biomolecules or fluorescent probes for research applications.

Basic Information

Product Name	(S)-3-Fluoro-1,2-Propanediol
CAS No.	33644-25-6
Molecular Formula	C3H7FO2
Molecular Weight	94.08 g/mol
Synonyms	(S)-3-Fluoropropane-1,2-diol; (S)-3-Fluoro-1,2-dihydroxypropane; (S)-3-Fluoropropylene Glycol; (S)-1,2-Dihydroxy-3-fluoropropane; (S)-3-Fluoropropanediol; (S)-3-Fluoro-propane-1,2-diol; (S)-3-Fluoro-1,2-propanediol; (S)-3-Fluoropropan-1,2-diol
EINECS	Contact for details

Quality Control

Our (S)-3-Fluoro-1,2-Propanediol is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to verify identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.