Description

(2S)-2-Phenyl-1-Butanol CAS NO 33442-47-6 is a chiral secondary alcohol characterized by its phenyl and butyl substituents, making it a valuable non-racemic building block in asymmetric synthesis. Its enantiopure nature is critical for producing compounds with high stereochemical fidelity, directly impacting the efficacy and safety profile of final products. This intermediate is essential for research and production in the pharmaceutical and fine chemical industries, where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of cardiovascular and central nervous system drugs.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize novel chiral ligands for transition metal catalysis, enhancing enantioselectivity in reactions.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, agrochemicals, and specialty materials requiring specific (S)-configuration.
• Flavor and Fragrance Industry: Serves as a starting material for creating enantiomerically pure aroma chemicals and flavor compounds.
• Academic and R&D: A standard reagent in university and corporate research laboratories for methodological studies in organic and medicinal chemistry.
• Material Science: Potential monomer or modifier in the synthesis of chiral polymers with specialized optical properties.

Basic Information

Product Name	(2S)-2-Phenyl-1-Butanol
CAS No.	33442-47-6
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(S)-2-Phenyl-1-butanol; (S)-(-)-2-Phenyl-1-butanol; (S)-2-Phenylbutan-1-ol; 1-Butanol, 2-phenyl-, (2S)-; L-2-Phenyl-1-butanol; (-)-2-Phenyl-1-butanol; (S)-1-Hydroxy-2-phenylbutane; Phenylbutanol
EINECS	Contact for details

Quality Control

Our (2S)-2-Phenyl-1-Butanol is manufactured under strict quality management systems. We provide material that meets high-purity standards, with typical specifications focusing on enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are available for every batch. Our quality commitment ensures reliability for your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from heat, sparks, and open flames. Due to its sensitivity to oxidation, containers should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.