Description

2,3,4,6-Tetrafluorobenzoic Acid is a highly fluorinated aromatic carboxylic acid derivative, serving as a critical building block in advanced chemical synthesis. Its unique perfluorinated substitution pattern makes it a valuable precursor for introducing fluorine atoms into complex molecules, significantly altering their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where precise fluorination is required to develop novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging fluorine's ability to increase lipophilicity and target binding affinity.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, improving thermal stability, dielectric anisotropy, and optical properties.
• Polymer & Resin Modification: Incorporated into specialty polymers to enhance chemical resistance, reduce surface energy, and improve weatherability for coatings and high-performance plastics.
• Organic Synthesis Reagent: Employed in coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a directing group or protecting group in complex multi-step synthetic routes.
• Fluorinated Surfactant & Lubricant Precursor: Used to synthesize surfactants and lubricants with superior stability and performance in extreme environments.

Basic Information

Product Name	2,3,4,6-Tetrafluorobenzoic Acid
CAS No.	32890-92-9
Molecular Formula	C7H2F4O2
Molecular Weight	194.09 g/mol
Synonyms	Benzoic acid, 2,3,4,6-tetrafluoro-; 2,3,4,6-Tetrafluorobenzenecarboxylic acid; Perfluorobenzoic acid (specific isomer); Tetrafluorobenzoic acid; TFB Acid; 2,3,4,6-TFBA; 32890-92-9; NSC 406915
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetrafluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and incompatible materials. Due to its acidic nature, appropriate chemical-resistant secondary containment is recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.