Description

1,2,4,6-Di-o-Isopropylidene-α-L-Sorbofuranose is a key chiral building block and protected sugar derivative widely used in fine chemical synthesis. Its primary value lies in its role as a versatile precursor for the production of high-value L-ascorbic acid (Vitamin C) and other biologically active compounds. This intermediate is essential for manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries seeking reliable, high-purity raw materials for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the commercial synthesis of L-ascorbic acid (Vitamin C) and its derivatives.
• Chiral Synthesis: Serves as a starting material or chiral auxiliary for the asymmetric synthesis of various active pharmaceutical ingredients (APIs).
• Nutraceutical Production: Used in the manufacturing of premium-grade Vitamin C for dietary supplements and fortified foods.
• Fine Chemical Research: Employed in R&D laboratories for developing new carbohydrate-based molecules and exploring novel synthetic routes.
• Glycochemistry: Acts as a protected sugar donor for the synthesis of complex carbohydrates, glycoconjugates, and nucleoside analogs.
• Cosmetic Ingredients: Potential intermediate in the production of certain stabilized Vitamin C derivatives used in skincare formulations.

Basic Information

Product Name	1,2,4,6-Di-o-Isopropylidene-α-L-Sorbofuranose
CAS No.	32717-65-0
Molecular Formula	C12H18O6
Molecular Weight	258.27 g/mol
Synonyms	1,2:4,6-Di-O-isopropylidene-α-L-sorbofuranose; Diacetone-L-sorbose; Diacetone sorbose; 2,3:4,6-Di-O-isopropylidene-α-L-sorbofuranose; L-Sorbose diacetonide; α-L-Sorbofuranose, 1,2:4,6-di-O-(1-methylethylidene)-; DAS
EINECS	251-212-0

Quality Control

Our 1,2,4,6-Di-o-Isopropylidene-α-L-Sorbofuranose is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, optical rotation, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply for critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.