Description

(-)-Diop CAS NO 32305-98-9 is a chiral organophosphorus compound widely recognized as a versatile ligand in asymmetric catalysis. Its primary value lies in its ability to induce high enantioselectivity in critical synthetic transformations, enabling the production of optically pure intermediates. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
• Catalyst component in enantioselective C-C bond-forming reactions, such as allylic alkylation.
• Use in academic and industrial R&D for developing novel catalytic asymmetric processes.
• Key reagent for the preparation of enantiomerically enriched compounds in fine chemical manufacturing.
• Potential application in material science for creating chiral molecular frameworks.

Basic Information

Product Name	(-)-Diop
CAS No.	32305-98-9
Molecular Formula	C31H32O2P2
Molecular Weight	498.53 g/mol
Synonyms	(-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane; (2R,3R)-(-)-Bis(diphenylphosphino)butane; (R,R)-(-)-DIOP; (-)-DIOP; (2R,3R)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol; (R,R)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol; DIOP ligand
EINECS	Contact for details

Quality Control

Our (-)-Diop is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling. A Certificate of Analysis (COA) detailing specific results for identity, assay, and enantiomeric excess is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 15-25°C. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.