Description

(4-Perfluorotolyl)Acetic Acid is a high-value fluorinated aromatic building block characterized by its perfluorinated methyl group attached to a phenylacetic acid core. This compound matters for its role in introducing lipophilic, electron-withdrawing, and chemically stable perfluoroaryl motifs into advanced molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries for applications in drug discovery, ligand synthesis, and the development of novel fluorinated polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring perfluoroaryl groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the fluorinated moiety enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a precursor in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and thermal stability.
• Polymer & Resin Modification: Employed to incorporate perfluorotolyl groups into polymer backbones or side chains, enhancing material properties such as chemical resistance, hydrophobicity, and dielectric performance.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated ligands for catalysis, where the electron-deficient aromatic ring influences metal center reactivity.
• Advanced Material Research: Functions as a building block in materials science for creating novel fluorinated surfaces, coatings, and nano-materials with unique interfacial properties.

Basic Information

Product Name	(4-Perfluorotolyl)Acetic Acid
CAS No.	32304-29-3
Molecular Formula	C9H3F7O2
Molecular Weight	276.11 g/mol
Synonyms	2-(Perfluoro-p-tolyl)acetic Acid; 2-(2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl)acetic Acid; 4-(Trifluoromethyl)tetrafluorophenylacetic Acid; α-(Perfluoro-p-tolyl)acetic Acid; p-(Perfluoromethyl)phenylacetic Acid; 4-(Perfluoromethyl)benzeneacetic Acid; (Perfluoro-4-methylphenyl)acetic Acid; (α-Carboxy-2,3,5,6-tetrafluoro-4-trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our (4-Perfluorotolyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.